Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_02_BT_ATM_minus_versus_ATM_plus.phenotype_BT_ATM_minus_versus_ATM_plus.cls #BT_ATM_minus_versus_ATM_plus.phenotype_BT_ATM_minus_versus_ATM_plus.cls #BT_ATM_minus_versus_ATM_plus_repos |
| Phenotype | phenotype_BT_ATM_minus_versus_ATM_plus.cls#BT_ATM_minus_versus_ATM_plus_repos |
| Upregulated in class | ATM_plus |
| GeneSet | BIOCARTA_ACTIONS OF NITRIC OXIDE IN THE HEART |
| Enrichment Score (ES) | -0.66464436 |
| Normalized Enrichment Score (NES) | -1.7595763 |
| Nominal p-value | 0.0078125 |
| FDR q-value | 0.21553387 |
| FWER p-Value | 0.859 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PIK3R1 | 1425514_at 1425515_at 1438682_at 1444591_at 1451737_at | 343 | 1.346 | 0.0817 | No | ||
| 2 | PRKAR1B | 1416753_at 1416754_at 1434325_x_at 1440132_s_at 1440133_x_at 1460073_at | 879 | 0.603 | 0.1010 | No | ||
| 3 | PIK3CA | 1423144_at 1429434_at 1429435_x_at 1440054_at 1453134_at 1460326_at | 1919 | 0.273 | 0.0733 | No | ||
| 4 | AKT1 | 1416657_at 1425711_a_at 1440950_at 1442759_at | 2060 | 0.252 | 0.0851 | No | ||
| 5 | PRKG2 | 1421354_at 1435162_at 1435460_at | 3007 | 0.161 | 0.0535 | No | ||
| 6 | PLCG1 | 1435149_at 1450360_at | 3957 | 0.117 | 0.0187 | No | ||
| 7 | BDKRB2 | 1422263_at 1442187_at | 4540 | 0.099 | -0.0008 | No | ||
| 8 | PRKAR2B | 1430640_a_at 1438664_at 1456475_s_at | 4847 | 0.090 | -0.0082 | No | ||
| 9 | FLT1 | 1419300_at 1440926_at 1451756_at 1454037_a_at | 5883 | 0.068 | -0.0505 | No | ||
| 10 | TNNI1 | 1450813_a_at | 6099 | 0.064 | -0.0557 | No | ||
| 11 | KNG1 | 1416676_at 1426045_at | 7071 | 0.047 | -0.0966 | No | ||
| 12 | CHRM1 | 1439611_at 1450833_at | 7689 | 0.037 | -0.1221 | No | ||
| 13 | CAV1 | 1449145_a_at | 7955 | 0.033 | -0.1318 | No | ||
| 14 | PDE3B | 1433694_at | 8288 | 0.029 | -0.1449 | No | ||
| 15 | PRKACB | 1420610_at 1420611_at 1457197_at | 8690 | 0.023 | -0.1615 | No | ||
| 16 | KDR | 1449379_at | 9034 | 0.018 | -0.1759 | No | ||
| 17 | GUCY1A3 | 1420533_at 1420534_at 1434141_at | 10007 | 0.005 | -0.2199 | No | ||
| 18 | GUCY2C | 1436370_at | 10115 | 0.004 | -0.2245 | No | ||
| 19 | PRKAR2A | 1427414_at 1428783_at 1432409_at 1445325_at 1452915_at | 11220 | -0.011 | -0.2741 | No | ||
| 20 | FLT4 | 1421442_at | 13453 | -0.041 | -0.3731 | No | ||
| 21 | GNGT1 | 1425167_a_at 1425168_at 1425219_x_at 1451633_a_at | 15403 | -0.072 | -0.4569 | No | ||
| 22 | PDE3A | 1431913_a_at 1431914_at 1445373_at 1450284_at | 15902 | -0.081 | -0.4738 | No | ||
| 23 | PRKG1 | 1443663_at 1443811_at 1443812_x_at 1444232_at 1445807_at 1445998_at 1449876_at | 16300 | -0.088 | -0.4855 | No | ||
| 24 | CAMK2B | 1448676_at 1455869_at | 16726 | -0.098 | -0.4978 | No | ||
| 25 | RYR2 | 1421126_at 1445498_at 1450123_at | 16990 | -0.105 | -0.5023 | No | ||
| 26 | HSP90AA1 | 1426645_at 1437497_a_at 1438902_a_at 1455078_at | 17352 | -0.114 | -0.5105 | No | ||
| 27 | GNAQ | 1428938_at 1428939_s_at 1428940_at 1429559_at 1446688_at 1447593_x_at 1450115_at 1455729_at 1458159_at | 17611 | -0.121 | -0.5135 | No | ||
| 28 | CHRNA1 | 1418852_at | 17736 | -0.125 | -0.5101 | No | ||
| 29 | NOS3 | 1422622_at | 17896 | -0.130 | -0.5080 | No | ||
| 30 | GUCY1A2 | 1459336_at | 18693 | -0.156 | -0.5330 | No | ||
| 31 | PDE2A | 1447707_s_at 1447708_x_at 1452202_at | 21576 | -0.835 | -0.6042 | Yes | ||
| 32 | PDPK1 | 1415729_at 1416501_at 1459775_at 1459776_x_at | 21590 | -0.858 | -0.5427 | Yes | ||
| 33 | PRKAR1A | 1425550_a_at 1447635_at 1452032_at | 21798 | -1.527 | -0.4416 | Yes | ||
| 34 | GUCY1B3 | 1420871_at 1420872_at | 21814 | -1.582 | -0.3278 | Yes | ||
| 35 | SLC7A1 | 1421533_at 1454991_at 1454992_at | 21885 | -1.934 | -0.1911 | Yes | ||
| 36 | GNB1 | 1417432_a_at 1425908_at 1454696_at 1459442_at | 21915 | -2.671 | 0.0009 | Yes |
